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Post-Genomics centre to hunt secrets of life
Housed in the university's Wellcome Trust Biocentre, the centre will work on the wealth of raw data that has emerged from the recent sequencing of the human genome and disease-causing microbes. The raw DNA (deoxyribonucleic acid) sequence of a human being is an unpunctuated string of three billion letters of four symbols (A, C, T and G). The process of compiling this sequence is known as genomics. The process of mining useful information from the "book of man" is known as post-genomics.
The investigators have already discovered that malaria and tuberculosis, which kill more than five million people annually, share a common enzyme with the E.coli bacterium that causes food poisoning. The Dundee researchers confidently predict a cure for the two diseases will be available within five years.
The amount of information revealed by the human genome project and its equivalents in other organisms such as the fruit fly is remarkable. Post-genomics is the science of quarrying that information, extracting what is useful and putting it to work in understanding and combating a variety of diseases.
"That is where post-genomics is right now. New technologies to accelerate that searching process have developed so fast and what was state-of-the-art two years ago is already regarded as primitive. So, the bringing together of the four key cutting-edge technologies and crucial and the scientists to use and develop them in one centre is highly significant for what is regarded as the next major new development in the international scientific world," he added. Published on 4th August, 2002 Source: London Press Service,
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